Forschungsschwerpunkte
Systematische Reviews, Adipositas & Diabetes Prävention
Aktuelle Forschungsprojekte
Cochrane reviews on food taxation, Systematic Review on community gardening for preventing overweight and obesity
Werdegang
- 05/2014-07/2019: Wissenschaftlicher Mitarbeiter an der Universität Bremen/ Leibniz-Institut für Präventionsforschung und Epidemiologie, kooperative Forschungsgruppe Evidence-Based Public Health
- 04/2017-05/2017: Gastwissenschaftler bei Public Health Insight und “Cochrane Public Health”, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australien
- 04/2007-12/2013: Studium Diplom Gesundheitsökonomie, Universität zu Köln
– Thema der Abschlussarbeit: „Kommunikationsprozesse am Lebensende: Advance care planning” - 10/2011-03/2012: Praktikum bei der „Cochrane Metabolic and Endocrine Disorders Group”, Heinrich Heine Universität Düsseldorf
– Thema der Projektarbeit: „Berücksichtigung patientenrelevanter Outcome-Parameter bei Zusammenfassungs- und Berichtsteil von systematischen Übersichtsarbeiten der Cochrane Collaboration“ - 02/2009-03/2009: Praktikum bei Birgitt Bender, Sprecherin für Gesundheitspolitik der Fraktion B’90/Die Grünen, Mitglied des Bundestages, Berlin, Germany
– Kleine Anfrage an die Bundesregierung: „Maßnahmen zur Rauchentwöhnung”
Detailierter CV
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Publikationen
2018 |
von Philipsborn, Peter; Stratil, Jan M; Heise, Thomas L; Landgraf, Rüdiger; Hauner, Hans; Rehfuess, Eva A Public Health Nutrition, S. 1–8, 2018. @article{philipsborn_stratil_heise_landgraf_hauner_rehfuess, title = {Voluntary industry initiatives to promote healthy diets: a case study on a major European food retailer}, author = {Peter von Philipsborn and Jan M Stratil and Thomas L Heise and Rüdiger Landgraf and Hans Hauner and Eva A Rehfuess}, url = {https://www.cambridge.org/core/journals/public-health-nutrition/article/voluntary-industry-initiatives-to-promote-healthy-diets-a-case-study-on-a-major-european-food-retailer}, doi = {10.1017/S1368980018002744}, year = {2018}, date = {2018-10-18}, journal = {Public Health Nutrition}, pages = {1–8}, publisher = {Cambridge University Press}, abstract = {OBJECTIVE: To analyse the scope and content of the nutrition pledge announced by Lidl. DESIGN: We applied the approach recommended by the private-sector module of the INFORMAS (International Network for Food and Obesity Research, Monitoring and Action Support) food environment monitoring framework and qualitative content analysis to Lidl's nutrition pledge. SETTING: Global. SUBJECTS: The nutrition pledge of Lidl, Europe's largest food retailer. RESULTS: Lidl pledges to reduce the average sales-weighted content of added sugar and added salt in its own-brand products by 20 % until 2025, using 2015 as a baseline, starting in Germany. Moreover, it vows to reduce the saturated and trans-fatty acid contents of its own-brand products, without specifying targets or timelines. To achieve these targets, it pledges to apply a number of approaches, including reformulation, promotion of healthier products, reduction of package and portion sizes, and provision of nutrition information and education. Strengths of Lidl's pledge are its extensive scope, the quantification of some targets, and its partially evidence-based approach to the selection of targets and interventions. Key limitations include the vagueness of many targets, a lack of transparency and the absence of independent monitoring and evaluation. CONCLUSIONS: Lidl's pledge, while commendable for its scope, does not meet current best practice guidelines. Given their current limitations, industry initiatives of this kind are likely to fall short of what is needed to improve population-level nutrition.}, keywords = {}, pubstate = {published}, tppubtype = {article} } OBJECTIVE: To analyse the scope and content of the nutrition pledge announced by Lidl. DESIGN: We applied the approach recommended by the private-sector module of the INFORMAS (International Network for Food and Obesity Research, Monitoring and Action Support) food environment monitoring framework and qualitative content analysis to Lidl's nutrition pledge. SETTING: Global. SUBJECTS: The nutrition pledge of Lidl, Europe's largest food retailer. RESULTS: Lidl pledges to reduce the average sales-weighted content of added sugar and added salt in its own-brand products by 20 % until 2025, using 2015 as a baseline, starting in Germany. Moreover, it vows to reduce the saturated and trans-fatty acid contents of its own-brand products, without specifying targets or timelines. To achieve these targets, it pledges to apply a number of approaches, including reformulation, promotion of healthier products, reduction of package and portion sizes, and provision of nutrition information and education. Strengths of Lidl's pledge are its extensive scope, the quantification of some targets, and its partially evidence-based approach to the selection of targets and interventions. Key limitations include the vagueness of many targets, a lack of transparency and the absence of independent monitoring and evaluation. CONCLUSIONS: Lidl's pledge, while commendable for its scope, does not meet current best practice guidelines. Given their current limitations, industry initiatives of this kind are likely to fall short of what is needed to improve population-level nutrition. |
Kebede, Mihiretu M; Zeeb, Hajo; Peters, Manuela; Heise, Thomas L; Pischke, Claudia R Diabetes Technology & Therapeutics, 2018. @article{doi:10.1089/dia.2018.0216, title = {Effectiveness of Digital Interventions for Improving Glycemic Control in Persons with Poorly Controlled Type 2 Diabetes: A Systematic Review, Meta-analysis, and Meta-regression Analysis}, author = {Mihiretu M. Kebede and Hajo Zeeb and Manuela Peters and Thomas L. Heise and Claudia R Pischke}, url = {https://doi.org/10.1089/dia.2018.0216}, doi = {10.1089/dia.2018.0216}, year = {2018}, date = {2018-09-26}, journal = {Diabetes Technology & Therapeutics}, abstract = {Abstract Background: Digital interventions may assist patients with type 2 diabetes in improving glycemic control. We aimed to synthesize effect sizes of digital interventions on glycated hemoglobin (HbA1c) levels and to identify effective features of digital interventions targeting patients with poorly controlled type 2 diabetes. Materials and Methods: MEDLINE, ISI Web of Science, and PsycINFO were searched for randomized controlled trials (RCTs) comparing the effects of digital interventions with usual care. Two reviewers independently assessed studies for eligibility and determined study quality, using the Cochrane Risk of Bias Assessment Tool. The Behavioral Change Technique Taxonomy V1 (BCTTv1) was used to identify BCTs used in interventions. Mean HbA1c differences were pooled using analysis of covariance to adjust for baseline differences and pre–post correlations. To examine effective intervention features and to evaluate differences in effect sizes across groups, meta-regression and subgroup analyses were performed. Results: Twenty-three arms of 21 RCTs were included in the meta-analysis (n = 3787 patients, 52.6% in intervention arms). The mean HbA1c baseline differences ranged from −0.2% to 0.64%. The pooled mean HbA1c change was statistically significant (−0.39 95% CI: [−0.51 to −0.26] with substantial heterogeneity [I2 statistic, 80.8%]) and a significant HbA1c reduction was noted for web-based interventions. A baseline HbA1c level above 7.5%, β = −0.44 (95% CI: [−0.81 to −0.06]), the BCTs “problem solving,” β = −1.30 (95% CI: [−2.05 to −0.54]), and “self-monitoring outcomes of behavior,” β = −1.21 (95% CI: [−1.95 to −0.46]) were significantly associated with reduced HbA1c levels. Conclusions: Digital interventions appear effective for reducing HbA1c levels in patients with poorly controlled type 2 diabetes.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Abstract Background: Digital interventions may assist patients with type 2 diabetes in improving glycemic control. We aimed to synthesize effect sizes of digital interventions on glycated hemoglobin (HbA1c) levels and to identify effective features of digital interventions targeting patients with poorly controlled type 2 diabetes. Materials and Methods: MEDLINE, ISI Web of Science, and PsycINFO were searched for randomized controlled trials (RCTs) comparing the effects of digital interventions with usual care. Two reviewers independently assessed studies for eligibility and determined study quality, using the Cochrane Risk of Bias Assessment Tool. The Behavioral Change Technique Taxonomy V1 (BCTTv1) was used to identify BCTs used in interventions. Mean HbA1c differences were pooled using analysis of covariance to adjust for baseline differences and pre–post correlations. To examine effective intervention features and to evaluate differences in effect sizes across groups, meta-regression and subgroup analyses were performed. Results: Twenty-three arms of 21 RCTs were included in the meta-analysis (n = 3787 patients, 52.6% in intervention arms). The mean HbA1c baseline differences ranged from −0.2% to 0.64%. The pooled mean HbA1c change was statistically significant (−0.39 95% CI: [−0.51 to −0.26] with substantial heterogeneity [I2 statistic, 80.8%]) and a significant HbA1c reduction was noted for web-based interventions. A baseline HbA1c level above 7.5%, β = −0.44 (95% CI: [−0.81 to −0.06]), the BCTs “problem solving,” β = −1.30 (95% CI: [−2.05 to −0.54]), and “self-monitoring outcomes of behavior,” β = −1.21 (95% CI: [−1.95 to −0.46]) were significantly associated with reduced HbA1c levels. Conclusions: Digital interventions appear effective for reducing HbA1c levels in patients with poorly controlled type 2 diabetes. |
Nussbaumer-Streit, Barbara; Klerings, Irma; Wagner, Gernot; Heise, Thomas L; Dobrescu, Andreea I; Armijo-Olivo, Susan; Stratil, Jan; Persad, Emma; Lhachimi, Stefan K; Noord, Megan Van; Mittermayr, Tarquin; Zeeb, Hajo; Hemkens, Lars; Gartlehner, Gerald Journal of Clinical Epidemiology, 102 , S. 1 - 11, 2018, ISSN: 0895-4356. @article{NUSSBAUMERSTREIT20181, title = {Abbreviated literature searches were viable alternatives to comprehensive searches: a meta-epidemiological study}, author = {Barbara Nussbaumer-Streit and Irma Klerings and Gernot Wagner and Thomas L Heise and Andreea I Dobrescu and Susan Armijo-Olivo and Jan Stratil and Emma Persad and Stefan K Lhachimi and Megan Van Noord and Tarquin Mittermayr and Hajo Zeeb and Lars Hemkens and Gerald Gartlehner}, url = {http://www.sciencedirect.com/science/article/pii/S0895435618300179}, doi = {10.1016/j.jclinepi.2018.05.022}, issn = {0895-4356}, year = {2018}, date = {2018-06-02}, journal = {Journal of Clinical Epidemiology}, volume = {102}, pages = {1 - 11}, abstract = {Objective To assess the effects of abbreviated literature searches on evidence syntheses conclusions. Study design and setting We randomly selected 60 Cochrane reviews of clinical interventions and repeated literature searches using 14 abbreviated approaches (combinations of MEDLINE, Embase, CENTRAL with and without searches of reference lists). If abbreviated searches missed included studies, we recalculated meta-analyses. Cochrane authors determined whether the new evidence base would change conclusions. We assessed the noninferiority of abbreviated searches allowing for a maximum of 10% changed conclusions. Results We conducted 840 abbreviated literature searches. Noninferiority varied based on the definition of “changed conclusion”. When the reduction of the certainty of a conclusion was of concern, all abbreviated searches were inferior. Searching Embase only rendered the greatest proportion of changed conclusions (27%, 95% confidence interval [CI]: 16%–40%); combining MEDLINE, Embase, CENTRAL with searches of references lists the lowest (8%, 95% CI 3%–18%). When falsely reaching an opposite conclusion was of concern, combining one database with another or with searches of reference lists was noninferior to comprehensive searches (2%, 95% CI: 0%–9%). Conclusion If decision-makers are willing to accept less certainty and a small risk for opposite conclusions, some abbreviated searches are viable options for rapid evidence syntheses. Decisions demanding high certainty require comprehensive searches.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Objective To assess the effects of abbreviated literature searches on evidence syntheses conclusions. Study design and setting We randomly selected 60 Cochrane reviews of clinical interventions and repeated literature searches using 14 abbreviated approaches (combinations of MEDLINE, Embase, CENTRAL with and without searches of reference lists). If abbreviated searches missed included studies, we recalculated meta-analyses. Cochrane authors determined whether the new evidence base would change conclusions. We assessed the noninferiority of abbreviated searches allowing for a maximum of 10% changed conclusions. Results We conducted 840 abbreviated literature searches. Noninferiority varied based on the definition of “changed conclusion”. When the reduction of the certainty of a conclusion was of concern, all abbreviated searches were inferior. Searching Embase only rendered the greatest proportion of changed conclusions (27%, 95% confidence interval [CI]: 16%–40%); combining MEDLINE, Embase, CENTRAL with searches of references lists the lowest (8%, 95% CI 3%–18%). When falsely reaching an opposite conclusion was of concern, combining one database with another or with searches of reference lists was noninferior to comprehensive searches (2%, 95% CI: 0%–9%). Conclusion If decision-makers are willing to accept less certainty and a small risk for opposite conclusions, some abbreviated searches are viable options for rapid evidence syntheses. Decisions demanding high certainty require comprehensive searches. |
2017 |
Ogurtsova, Katherine; Heise, Thomas L; Linnenkamp, Ute; Dintsios, Charalabos-Markos; Lhachimi, Stefan K; Icks, Andrea Systematic Reviews, 6 (1), S. 1-10, 2017, ISSN: 2046-4053. @article{Ogurtsova2017, title = {External validation of type 2 diabetes computer simulation models: definitions, approaches, implications and room for improvement - a protocol for a systematic review}, author = {Katherine Ogurtsova and Thomas L Heise and Ute Linnenkamp and Charalabos-Markos Dintsios and Stefan K Lhachimi and Andrea Icks}, url = {https://doi.org/10.1186/s13643-017-0664-7}, issn = {2046-4053}, year = {2017}, date = {2017-12-29}, journal = {Systematic Reviews}, volume = {6}, number = {1}, pages = {1-10}, abstract = {Type 2 diabetes mellitus (T2DM), a highly prevalent chronic disease, puts a large burden on individual health and health care systems. Computer simulation models, used to evaluate the clinical and economic effectiveness of various interventions to handle T2DM, have become a well-established tool in diabetes research. Despite the broad consensus about the general importance of validation, especially external validation, as a crucial instrument of assessing and controlling for the quality of these models, there are no systematic reviews comparing such validation of diabetes models. As a result, the main objectives of this systematic review are to identify and appraise the different approaches used for the external validation of existing models covering the development and progression of T2DM.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Type 2 diabetes mellitus (T2DM), a highly prevalent chronic disease, puts a large burden on individual health and health care systems. Computer simulation models, used to evaluate the clinical and economic effectiveness of various interventions to handle T2DM, have become a well-established tool in diabetes research. Despite the broad consensus about the general importance of validation, especially external validation, as a crucial instrument of assessing and controlling for the quality of these models, there are no systematic reviews comparing such validation of diabetes models. As a result, the main objectives of this systematic review are to identify and appraise the different approaches used for the external validation of existing models covering the development and progression of T2DM. |
Khan, Zohaib; Suliankatchi, Rizwan Abdulkader; Heise, Thomas L; Dreger, Steffen Nicotine & Tobacco Research, S. ntx281, 2017. @article{Khan2017, title = {Naswar (Smokeless Tobacco) Use and the Risk of Oral Cancer in Pakistan: A systematic Review with meta-analysis}, author = {Zohaib Khan and Rizwan Abdulkader Suliankatchi and Thomas L Heise and Steffen Dreger}, url = {https://doi.org/10.1093/ntr/ntx281}, year = {2017}, date = {2017-12-25}, journal = {Nicotine & Tobacco Research}, pages = {ntx281}, abstract = {Introduction With an annual increase of 16,000 new cases each year, oral cancer is the second most common cancer in Pakistan. There is conflicting evidence regarding the carcinogenicity of different forms of smokeless tobacco (SLT) from different countries. This difference in evidence may be attributed to the varied composition of SLT products used around the world, necessitating the establishment of individual risks related to each SLT product. Methods An electronic search in relevant databases yielded 119 publications, out of which 6 were included in this review. Effect estimates (odds ratios (OR)) were abstracted or calculated from the given data. A fixed effects meta-analysis was performed to assess the risk of oral cancer with the use of Naswar. Population attributable fractions (PAF) were also calculated. Results The Meta Odds Ratio (mOR) for oral cancer associated with the “ever use” of Naswar compared to “never use” was 11.8 (95% CI, 8.4-16.4), I2 = 67%. The pooled estimate for oral cancer in “Ever-users” of Naswar compared to “Never-users”, in the Khyber Pakhtunkhwa province was 18.3 (95% CI, 8.7-38.5), I2 = 0%. The PAF for oral cancer associated with the use of Naswar in Pakistan was 44% (95% CI, 35%-53%). Discussion This review highlights a strong relationship between oral cancer incidence and the use of Naswar in Pakistan and adds to the evidence base on the carcinogenicity of SLT products in humans. Although the synthesized evidence may not be of a high quality, it represents the “best available evidence” which can be used to inform policy. Implications The carcinogenicity of Naswar, a form of smokeless tobacco used extensively in Pakistan, Afghanistan and Central Asia, has yet to be recognized by the International Agency for Research on Cancer (IARC), partly due to the lack of evidence on the association of Naswar use and cancer. Additionally, Naswar is as yet un-regulated in Pakistan and evades the tax net, resulting in it being freely available to both adults and children at very cheap prices compared to cigarettes, which has been the main focus of tobacco control in Pakistan. This review provides ample evidence for the IARC to declare Naswar as carcinogenic, as well as the Government of Pakistan to regulate the production and sale of Naswar.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Introduction With an annual increase of 16,000 new cases each year, oral cancer is the second most common cancer in Pakistan. There is conflicting evidence regarding the carcinogenicity of different forms of smokeless tobacco (SLT) from different countries. This difference in evidence may be attributed to the varied composition of SLT products used around the world, necessitating the establishment of individual risks related to each SLT product. Methods An electronic search in relevant databases yielded 119 publications, out of which 6 were included in this review. Effect estimates (odds ratios (OR)) were abstracted or calculated from the given data. A fixed effects meta-analysis was performed to assess the risk of oral cancer with the use of Naswar. Population attributable fractions (PAF) were also calculated. Results The Meta Odds Ratio (mOR) for oral cancer associated with the “ever use” of Naswar compared to “never use” was 11.8 (95% CI, 8.4-16.4), I2 = 67%. The pooled estimate for oral cancer in “Ever-users” of Naswar compared to “Never-users”, in the Khyber Pakhtunkhwa province was 18.3 (95% CI, 8.7-38.5), I2 = 0%. The PAF for oral cancer associated with the use of Naswar in Pakistan was 44% (95% CI, 35%-53%). Discussion This review highlights a strong relationship between oral cancer incidence and the use of Naswar in Pakistan and adds to the evidence base on the carcinogenicity of SLT products in humans. Although the synthesized evidence may not be of a high quality, it represents the “best available evidence” which can be used to inform policy. Implications The carcinogenicity of Naswar, a form of smokeless tobacco used extensively in Pakistan, Afghanistan and Central Asia, has yet to be recognized by the International Agency for Research on Cancer (IARC), partly due to the lack of evidence on the association of Naswar use and cancer. Additionally, Naswar is as yet un-regulated in Pakistan and evades the tax net, resulting in it being freely available to both adults and children at very cheap prices compared to cigarettes, which has been the main focus of tobacco control in Pakistan. This review provides ample evidence for the IARC to declare Naswar as carcinogenic, as well as the Government of Pakistan to regulate the production and sale of Naswar. |
Lhachimi, Stefan K; Heise, Thomas L Die Zuckersteuer – Mittel zur breitenwirksamen Prävention von Adipositas? Artikel Ernährung im Fokus, 17 (6), S. 318-321, 2017. @article{Lhachimi2017b, title = {Die Zuckersteuer – Mittel zur breitenwirksamen Prävention von Adipositas?}, author = {Stefan K. Lhachimi and Thomas L. Heise}, editor = {Bundeszentrum für Ernährung}, url = {https://www.bzfe.de/_data/files/leseprobe_5786_2017_eif.pdf}, year = {2017}, date = {2017-11-01}, journal = {Ernährung im Fokus}, volume = {17}, number = {6}, pages = {318-321}, abstract = {Die Idee einer Steuer auf hochkalorische fett- und zuckerreiche Lebensmittel (oft einfach „fat tax“ genannt) oder zumindest auf Süßgetränke ist zurzeit in aller Munde. Obwohl die zugrundeliegende ökonomische Theorie sowie die bekannten Vergleichsbeispiele Alkohol und Tabaksteuern in ihren Aussagen recht eindeutig sind, steckt der Teufel im Detail.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Die Idee einer Steuer auf hochkalorische fett- und zuckerreiche Lebensmittel (oft einfach „fat tax“ genannt) oder zumindest auf Süßgetränke ist zurzeit in aller Munde. Obwohl die zugrundeliegende ökonomische Theorie sowie die bekannten Vergleichsbeispiele Alkohol und Tabaksteuern in ihren Aussagen recht eindeutig sind, steckt der Teufel im Detail. |
Kebede, Mihiretu; Christianson, Lara; Khan, Zohaib; Heise, Thomas L; Pischke, Claudia R Systematic Reviews, 6 (1), S. 211, 2017, ISSN: 2046-4053. @article{Kebede2017, title = {Effectiveness of behavioral change techniques employed in eHealth interventions designed to improve glycemic control in persons with poorly controlled type 2 diabetes: a systematic review and meta-analysis protocol}, author = {Mihiretu Kebede and Lara Christianson and Zohaib Khan and Thomas L. Heise and Claudia R. Pischke}, url = {https://doi.org/10.1186/s13643-017-0609-1}, doi = {10.1186/s13643-017-0609-1}, issn = {2046-4053}, year = {2017}, date = {2017-10-24}, journal = {Systematic Reviews}, volume = {6}, number = {1}, pages = {211}, abstract = {The incorporation of Behavioral Change Techniques (BCTs) in eHealth interventions for the management of non-communicable diseases (NCDs), such as type 2 diabetes mellitus (T2DM), might be a promising approach to improve clinical and behavioral outcomes of NCDs in the long run. This 3paper reports a protocol for a systematic review that aims to (a) identify the effects of individual BCTs in eHealth interventions for lowering glycated hemoglobin levels (HbA1c) and (b) investigate which additional intervention features (duration of intervention, tailoring, theory-base, and mode of delivery) affect levels of HbA1c in this population. The protocol follows the Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) 2015 guideline.}, keywords = {}, pubstate = {published}, tppubtype = {article} } The incorporation of Behavioral Change Techniques (BCTs) in eHealth interventions for the management of non-communicable diseases (NCDs), such as type 2 diabetes mellitus (T2DM), might be a promising approach to improve clinical and behavioral outcomes of NCDs in the long run. This 3paper reports a protocol for a systematic review that aims to (a) identify the effects of individual BCTs in eHealth interventions for lowering glycated hemoglobin levels (HbA1c) and (b) investigate which additional intervention features (duration of intervention, tailoring, theory-base, and mode of delivery) affect levels of HbA1c in this population. The protocol follows the Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) 2015 guideline. |
Lhachimi, Stefan K; Heise, Thomas L impu!se für Gesundheitsförderung, 25 (96), S. 7-8, 2017, ISSN: 1438-6666. @article{Lhachimi2017, title = {Lebensmittelbesteuerung zur Prävention von Adipositas? Zwischen staatlichem Eingriff, persönlicher Freiheit und industriellen Interessen}, author = {Stefan K Lhachimi and Thomas L Heise}, url = {http://www.gesundheit-nds.de/images/pdfs/impulse/LVG-Zeitschrift-Nr96-Web.pdf}, issn = {1438-6666}, year = {2017}, date = {2017-09-15}, journal = {impu!se für Gesundheitsförderung}, volume = {25}, number = {96}, pages = {7-8}, abstract = {Es ist keine wirklich neue Erkenntnis, dass in Deutschland jeder zweite Erwachsene übergewichtig und fast jede vierte erwachsene Person von Adipositas betroffen ist. Es handelt sich hierbei um ein stetig zunehmendes Massenphänomen, verbunden mit großem individuellen Krankheitsleid und negativen gesamtgesellschaftlichen Folgen, welches sich in Teilen schon im Kindes- bzw. Jugendalter manifestiert. Gerade bei der Adipositas und ihren Folgeerkrankungen, insbesondere Diabetes Typ 2, sind die Zusammenhänge komplex und entziehen sich somit einfacher Erklärungsmodelle. Gleichzeitig entstehen hohe Gesundheitskosten: Die Gesamtkosten von Übergewicht und Adipositas beziffern sich in Deutschland zusammen auf 16,8 Mrd. Euro für das Jahr 2008. Im vereinfacht ausgedrückten Zusammenspiel zwischen zu geringer körperlicher Aktivität und zu hoher Energiezufuhr einer Person sind kalorienreiche Lebensmittel, insbesondere fett- und zuckerhaltige Lebensmittel, nun in den Fokus der internationalen Diskussion hinsichtlich der Ursachenbekämpfung nichtübertragbarer Krankheiten gerückt.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Es ist keine wirklich neue Erkenntnis, dass in Deutschland jeder zweite Erwachsene übergewichtig und fast jede vierte erwachsene Person von Adipositas betroffen ist. Es handelt sich hierbei um ein stetig zunehmendes Massenphänomen, verbunden mit großem individuellen Krankheitsleid und negativen gesamtgesellschaftlichen Folgen, welches sich in Teilen schon im Kindes- bzw. Jugendalter manifestiert. Gerade bei der Adipositas und ihren Folgeerkrankungen, insbesondere Diabetes Typ 2, sind die Zusammenhänge komplex und entziehen sich somit einfacher Erklärungsmodelle. Gleichzeitig entstehen hohe Gesundheitskosten: Die Gesamtkosten von Übergewicht und Adipositas beziffern sich in Deutschland zusammen auf 16,8 Mrd. Euro für das Jahr 2008. Im vereinfacht ausgedrückten Zusammenspiel zwischen zu geringer körperlicher Aktivität und zu hoher Energiezufuhr einer Person sind kalorienreiche Lebensmittel, insbesondere fett- und zuckerhaltige Lebensmittel, nun in den Fokus der internationalen Diskussion hinsichtlich der Ursachenbekämpfung nichtübertragbarer Krankheiten gerückt. |
Heise, Thomas L; Romppel, Matthias; Molnar, Sandra; Buchberger, Barbara; van den Berg, Agnes; Gartlehner, Gerald; Lhachimi, Stefan K BMJ Open, 7 (6), 2017, ISSN: 2044-6055. @article{Heisee016237, title = {Community gardening, community farming and other local community-based gardening interventions to prevent overweight and obesity in high-income and middle-income countries: protocol for a systematic review}, author = { Thomas L Heise and Matthias Romppel and Sandra Molnar and Barbara Buchberger and Agnes van den Berg and Gerald Gartlehner and Stefan K Lhachimi}, url = {http://bmjopen.bmj.com/content/7/6/e016237}, doi = {10.1136/bmjopen-2017-016237}, issn = {2044-6055}, year = {2017}, date = {2017-06-16}, journal = {BMJ Open}, volume = {7}, number = {6}, publisher = {British Medical Journal Publishing Group}, abstract = {Introduction: The worldwide prevalence of overweight/obesity has continued to rise over the last decades. To reverse this trend, public health authorities are exploring cost-effective interventions, especially in high-income and middle-income countries. Community gardening offers a unique opportunity for individuals to enhance physical activity levels and improve their diet. However, synthesised evidence on the short-term or long-term effectiveness and on the costs of community gardening interventions to prevent overweight/obesity remains limited. Therefore, this review will investigate: (1) the effectiveness of voluntary participation in community gardening compared with no or a control intervention on overweight/obesity and associated health outcomes, (2) effects on different subgroups of populations and (3) the costs of community gardening interventions. Methods and analysis: We will conduct a systematic review, limited to evaluations of community gardening interventions with controlled quantitative and interrupted time series designs. To identify relevant articles, we will systematically search 12 academic and 5 grey literature databases, as well as 2 trial registers and 6 websites. Articles will then be assessed for eligibility based on a predefined set of criteria. At least two independent reviewers will assess each article for relevance, before evaluating the methodological quality and potential bias of the studies. Data relevant to the objectives of this review will be extracted and cross-validated. Any disagreements will be mediated by a third reviewer. If feasible, meta-analyses of primary outcomes (overweight/obesity, physical activity, food intake, energy intake) will be conducted. We will use the Grading of Recommendations Assessment, Development and Evaluation method to assess the overall quality of evidence. Ethics and dissemination: For this review, no ethical approval is required as we will only extract and analyse secondary data. We aim to submit the final review manuscript to an open access journal for publication and disseminate results via conferences and social media. Trial registration number: International Prospective Register of Systematic Reviews (PROSPERO)(CRD42017043696).}, keywords = {}, pubstate = {published}, tppubtype = {article} } Introduction: The worldwide prevalence of overweight/obesity has continued to rise over the last decades. To reverse this trend, public health authorities are exploring cost-effective interventions, especially in high-income and middle-income countries. Community gardening offers a unique opportunity for individuals to enhance physical activity levels and improve their diet. However, synthesised evidence on the short-term or long-term effectiveness and on the costs of community gardening interventions to prevent overweight/obesity remains limited. Therefore, this review will investigate: (1) the effectiveness of voluntary participation in community gardening compared with no or a control intervention on overweight/obesity and associated health outcomes, (2) effects on different subgroups of populations and (3) the costs of community gardening interventions. Methods and analysis: We will conduct a systematic review, limited to evaluations of community gardening interventions with controlled quantitative and interrupted time series designs. To identify relevant articles, we will systematically search 12 academic and 5 grey literature databases, as well as 2 trial registers and 6 websites. Articles will then be assessed for eligibility based on a predefined set of criteria. At least two independent reviewers will assess each article for relevance, before evaluating the methodological quality and potential bias of the studies. Data relevant to the objectives of this review will be extracted and cross-validated. Any disagreements will be mediated by a third reviewer. If feasible, meta-analyses of primary outcomes (overweight/obesity, physical activity, food intake, energy intake) will be conducted. We will use the Grading of Recommendations Assessment, Development and Evaluation method to assess the overall quality of evidence. Ethics and dissemination: For this review, no ethical approval is required as we will only extract and analyse secondary data. We aim to submit the final review manuscript to an open access journal for publication and disseminate results via conferences and social media. Trial registration number: International Prospective Register of Systematic Reviews (PROSPERO)(CRD42017043696). |
von Philipsborn, Peter; Heise, Thomas L; Lhachimi, Stefan K; Landgraf, Rüdiger; Hauner, Hans Adipositas-Prävention: Eine Steuer auf Süßgetränke ist an der Zeit Artikel Deutsches Ärzteblatt International, 114 (4), S. A-160-5, 2017. @article{DAE186014, title = {Adipositas-Prävention: Eine Steuer auf Süßgetränke ist an der Zeit}, author = {Peter von Philipsborn and Thomas L Heise and Stefan K Lhachimi and Rüdiger Landgraf and Hans Hauner}, url = {http://www.aerzteblatt.de/int/article.asp?id=186014}, year = {2017}, date = {2017-01-27}, journal = {Deutsches Ärzteblatt International}, volume = {114}, number = {4}, pages = {A-160-5}, abstract = {Mexiko, Kalifornien, Frankreich und Großbritannien und andere haben vorgemacht, wie sich Süßgetränkesteuern für eine wirkungsvolle Primärprävention nutzen lassen. Jetzt ist es an der Zeit, dass Deutschland diesem guten Beispiel folgt.}, keywords = {}, pubstate = {published}, tppubtype = {article} } Mexiko, Kalifornien, Frankreich und Großbritannien und andere haben vorgemacht, wie sich Süßgetränkesteuern für eine wirkungsvolle Primärprävention nutzen lassen. Jetzt ist es an der Zeit, dass Deutschland diesem guten Beispiel folgt. |
2016 |
Lhachimi, Stefan K; Pega, Frank ; Heise, Thomas L; Fenton, Candida ; Gartlehner, Gerald ; Griebler, Ursula ; Sommer, Isolde ; Pfinder, Manuela ; Katikireddi, Srinivasa V Cochrane Database of Systematic Reviews, (10), 2016, ISSN: 1465-1858. @article{RN1, title = {Taxation of the fat content of foods for reducing their consumption and preventing obesity or other adverse health outcomes [Protocol]}, author = { Stefan K Lhachimi and Frank Pega and Thomas L Heise and Candida Fenton and Gerald Gartlehner and Ursula Griebler and Isolde Sommer and Manuela Pfinder and Srinivasa V Katikireddi}, url = {http://dx.doi.org/10.1002/14651858.CD012415}, issn = {1465-1858}, year = {2016}, date = {2016-10-28}, journal = {Cochrane Database of Systematic Reviews}, number = {10}, abstract = {This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of taxation of fat content in food on consumption of total fat and saturated fat, energy intake, overweight, obesity, and other adverse health outcomes in the general population.}, keywords = {}, pubstate = {published}, tppubtype = {article} } This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of taxation of fat content in food on consumption of total fat and saturated fat, energy intake, overweight, obesity, and other adverse health outcomes in the general population. |
Pfinder, Manuela; Katikireddi, Srinivasa V; Pega, Frank; Gartlehner, Gerald; Fenton, Candida; Griebler, Ursula; Sommer, Isolde; Heise, Thomas L; Lhachimi, Stefan K Cochrane Database of Systematic Reviews, (8), 2016, ISSN: 1465-1858. @article{RN1282, title = {Taxation of unprocessed sugar or sugar-added foods for reducing their consumption and preventing obesity or other adverse health outcomes [Protocol]}, author = {Manuela Pfinder and Srinivasa V. Katikireddi and Frank Pega and Gerald Gartlehner and Candida Fenton and Ursula Griebler and Isolde Sommer and Thomas L. Heise and Stefan K. Lhachimi}, url = {http://dx.doi.org/10.1002/14651858.CD012333}, issn = {1465-1858}, year = {2016}, date = {2016-08-29}, journal = {Cochrane Database of Systematic Reviews}, number = {8}, abstract = {This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of taxation of unprocessed sugar or sugar-added foods in the general population on the: 1. consumption of unprocessed sugar or sugar-added foods; 2. prevalence and incidence of overweight and obesity; and 3. prevalence and incidence of diet-related health conditions.}, keywords = {}, pubstate = {published}, tppubtype = {article} } This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of taxation of unprocessed sugar or sugar-added foods in the general population on the: 1. consumption of unprocessed sugar or sugar-added foods; 2. prevalence and incidence of overweight and obesity; and 3. prevalence and incidence of diet-related health conditions. |
Heise, Thomas L; Katikireddi, Srinivasa V; Pega, Frank ; Gartlehner, Gerald ; Fenton, Candida ; Griebler, Ursula ; Sommer, Isolde ; Pfinder, Manuela ; Lhachimi, Stefan K Cochrane Database of Systematic Reviews, (8), 2016, ISSN: 1465-1858. @article{RN948, title = {Taxation of sugar-sweetened beverages for reducing their consumption and preventing obesity or other adverse health outcomes [Protocol]}, author = { Thomas L. Heise and Srinivasa V. Katikireddi and Frank Pega and Gerald Gartlehner and Candida Fenton and Ursula Griebler and Isolde Sommer and Manuela Pfinder and Stefan K. Lhachimi}, url = {http://dx.doi.org/10.1002/14651858.CD012319}, issn = {1465-1858}, year = {2016}, date = {2016-08-17}, journal = {Cochrane Database of Systematic Reviews}, number = {8}, abstract = {This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of taxation of sugar-sweetened beverages (SSBs) on SSB consumption, energy intake, overweight, obesity, and other adverse health outcomes in the general population.}, keywords = {}, pubstate = {published}, tppubtype = {article} } This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of taxation of sugar-sweetened beverages (SSBs) on SSB consumption, energy intake, overweight, obesity, and other adverse health outcomes in the general population. |
Lhachimi, Stefan K; Busert, Laura K; Flatz, Aline ; Gartlehner, Gerald ; Griebler, Ursula ; Heise, Thomas L; Mütsch, Margot ; Rehfuess, Eva A Reaching out to Europe – Cochrane Public Health Europe and its research agenda Artikel Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen, 110-111 , S. 104-6, 2016, ISSN: 1865-9217. @article{tagkey2016, title = {Reaching out to Europe – Cochrane Public Health Europe and its research agenda}, author = {Lhachimi, Stefan K and Busert, Laura K and Flatz, Aline and Gartlehner, Gerald and Griebler, Ursula and Heise, Thomas L and Mütsch, Margot and Rehfuess, Eva A}, url = {http://www.sciencedirect.com/science/article/pii/S1865921715300039}, issn = {1865-9217}, year = {2016}, date = {2016-01-01}, journal = {Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen}, volume = {110-111}, pages = {104-6}, key = {tagkey2015}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
2014 |
Heise, Thomas Kommunikationsprozesse am Lebensende: Advance Care Planning Abschlussarbeit ElliNet, ZBMED Köln, 2014. @mastersthesis{Heise2014, title = {Kommunikationsprozesse am Lebensende: Advance Care Planning}, author = {Heise, Thomas}, url = {http://dx.doi.org/10.4126/38m-005445287}, year = {2014}, date = {2014-01-31}, school = {ElliNet, ZBMED Köln}, keywords = {}, pubstate = {published}, tppubtype = {mastersthesis} } |